BioCompatibility Innovation (BCI) is a company founded in 2014 and regularly registered in the Italian National Register of Innovative Start-ups. BCI operates in the biomedical and biotechnology fields and has focused mainly on the development of new technologies for the improvement of the biocompatibility degree of biological implantable medical devices and food from animal origins.

Biocompatibility improvements of bioprosthetic tissues

With particular reference to biological implantable biomedical devices, BCI has made its efforts in the field of bioprosthetic heart valves substitutes (BHVs). BCI designed and developed two patented processes for the treatment of soft animal tissues currently used to BHVs manufacture with the aim to increase their duration. The treatment called FACTA is effective for the inactivation of a particular antigenic epitope: the alpha-Gal molecule. Such xenogeneic antigen resulted present in mammalian animal tissues (except in humans and higher primates) and is responsible for the onset of dystrophic phenomena that affect the behaviour of commercially available BHVs, limiting their life to about 10/12 years from the implant thus obliging both surgeons to a repetitive replacement of the prosthesis and patients to an even burdensome surgery.

28 October 2020

Facta, the technology that doubles the life of heart valves

A Made in Italy technology that allows the doubling of the life of biological heart valves. The solution was developed by BCI, the innovative company led […]
10 July 2020

BCI joins Unismart, the community that promotes the technology transfer and innovation

Eighty-five highly specialized ventures including companies, research centers, and trade associations. Over 70 valued patents. A community where cross-contamination of ideas generates new business projects. A […]
10 July 2020

Interview with Alessandro Gandaglia – MIB Trieste School of Management

“My name is Alessandro Gandaglia and I’m the CEO of Biocompatibility Innovation. This video is in Italian, performed in 2018 as a testimonial for the Business […]